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apalutamide will minimize the extent or impact of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Prevent or Use Alternate Drug. Coadministration of apalutamide, a solid CYP2C19 inducer, with prescription drugs which might be CYP2C19 substrates can lead to decreased exposure to these remedies.Infants born to mothers employing benzodiazep